Cancer genomics.
نویسنده
چکیده
The draft human genome sequence and the dissemination of high throughput technology provides opportunities for systematic analysis of cancer cells. Genome-wide mutation screens, high resolution analysis of chromosomal abberations and expression profiling all give comprehensive views of genetic alterations in cancer cells. From these analyses will come a complete list of the genetic changes that drive malignant transformation and of the therapeutic targets that may be exploited for clinical benefit.
منابع مشابه
Review of State Comprehensive Cancer Control Plans for Genomics Content
INTRODUCTION The goals of this study were to determine U.S. states with Comprehensive Cancer Control plans that include genomics in some capacity and to review successes with and barriers to implementation of genomics-related cancer control initiatives. METHODS This study was conducted in two phases. Phase one included a content analysis of written state Comprehensive Cancer Control plans (n ...
متن کاملCancer Genomics Object Model: An Object Model for Multiple Functional Genomics Data for Cancer Research
The development of functional genomics including transcriptomics, proteomics and metabolomics allow us to monitor a large number of key cellular pathways simultaneously. Several technology-specific data models have been introduced for the representation of functional genomics experimental data, including the MicroArray Gene Expression-Object Model (MAGE-OM), the Proteomics Experiment Data Repos...
متن کاملApplication of Cancer Genomics to Solve Unmet Clinical Needs
The large amount of data on cancer genome research has contributed to our understanding of cancer biology. Indeed, the genomics approach has a strong advantage for analyzing multi-factorial and complicated problems, such as cancer. It is time to think about the actual usage of cancer genomics in the clinical field. The clinical cancer field has lots of unmet needs in the management of cancer pa...
متن کاملThe cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data.
The cBio Cancer Genomics Portal (http://cbioportal.org) is an open-access resource for interactive exploration of multidimensional cancer genomics data sets, currently providing access to data from more than 5,000 tumor samples from 20 cancer studies. The cBio Cancer Genomics Portal significantly lowers the barriers between complex genomic data and cancer researchers who want rapid, intuitive, ...
متن کاملGenoCache: a Genomics and Cancer Chemoprevention Portal
To integrate cancer chemoprevention information on a genomics basis, we have built a Web site named GenoCache (Genomics and Cancer Chemoprevention) that would provide users with a molecular biological view of cancer chemoprevention. The site is organized in four viewpoints: substances, genes or gene products with their genetic variations, cells or tissues with various cancer development states,...
متن کاملCNIO Cancer Conference Animal Tumour Models and Functional Genomics
s-Sessions Session I: Stem Cells and Cancer 17 Session II: Functional Genomics and Cancer Targets 24 Session III: Oncogenes and Tumour Suppressors 29 Session IV: Genetic Instability 37 Session V: Invasion and Metastasis 42
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Cancer cell
دوره 1 1 شماره
صفحات -
تاریخ انتشار 2002